They can inhibit both the innate and adaptive immune responses in addition to having a transdifferentiation capacity, which means that they are able to transform from one cell type to another into neuron-like cells.Ĭlinical studies have proven the beneficial capacities of MSCs, such as the ability to: Mesenchymal stem cells have immunomodulatory, immunosuppressive and repair functions. Mesenchymal stem cells are self-replicating cells that have shown in different studies to have the ability to suppress the effects on T cell proliferation and to reduce clinical scores, demyelination and inflammatory infiltrates in the central nervous system. They can be derived from bone marrow, adipose tissue, umbilical cord, placenta tissue and other sources. The most promising and beneficial approach uses mesenchymal stem cells (MSCs) because of their immunomodulation potential, safety and simplicity to obtain. One of the treatment options currently being used is stem cell therapy with mesenchymal stem cells. Because of the difficulty and the inability of current treatments to stop progressive neurodegenerative changes, alternative therapies are being evaluated. However, treatments can help speed recovery from attacks, modify the course of the disease and manage symptoms. Some people with severe MS may lose the ability to walk independently or at all, while others may experience long periods of remission without any new symptoms. Signs and symptoms of MS vary widely and depend on the amount of nerve damage and which nerves are affected. Eventually, the disease can cause permanent damage or deterioration of the nerves.
In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body.
Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system).
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